Basic Information
| Dataset | GSE174483 |
|---|---|
| Status | 2022-03-16 |
| Species | Mus musculus |
| Source | NCBI GEO |
| Subcellular Localization | nucleus|cytoplasm |
| PMID | 35358280 |
| Title | Nuclear and cytoplasmic whole transcriptome RNA-sequencing of mouse endothelial cell line and mmu-miR-466c knock-down cell line |
| Citation | Laitinen P, Väänänen MA, Kolari IL, Mäkinen PI et al. Nuclear microRNA-466c regulates Vegfa expression in response to hypoxia. PLoS One 2022;17(3):e0265948. |
| Experimental Design | Two cell lines (C166 wildtype and C1.1 mutant cell lines) were cultured in normoxia or hypoxia (2h and 24h timepoints) and split to nuclear and cytoplasmic fractions. All samples were done in triplicate. |
Sample Information
| BioProject | Sample Name | Localization | Treatment | Source | Label |
|---|---|---|---|---|---|
| PRJNA730029 | GSM5315716 | cytoplasm | normoxia | C166 endothelial cell line | C166_0hr_cyt_1 |
| PRJNA730029 | GSM5315717 | cytoplasm | normoxia | C166 endothelial cell line | C166_0hr_cyt_2 |
| PRJNA730029 | GSM5315718 | cytoplasm | normoxia | C166 endothelial cell line | C166_0hr_cyt_3 |
| PRJNA730029 | GSM5315719 | cytoplasm | 2h hypoxia | C166 endothelial cell line | C166_2hr_cyt_1 |
| PRJNA730029 | GSM5315720 | cytoplasm | 2h hypoxia | C166 endothelial cell line | C166_2hr_cyt_2 |
| PRJNA730029 | GSM5315721 | cytoplasm | 2h hypoxia | C166 endothelial cell line | C166_2hr_cyt_3 |
| PRJNA730029 | GSM5315722 | cytoplasm | 24h hypoxia | C166 endothelial cell line | C166_24hr_cyt_1 |
| PRJNA730029 | GSM5315723 | cytoplasm | 24h hypoxia | C166 endothelial cell line | C166_24hr_cyt_2 |
| PRJNA730029 | GSM5315724 | cytoplasm | 24h hypoxia | C166 endothelial cell line | C166_24hr_cyt_3 |
| PRJNA730029 | GSM5315725 | cytoplasm | normoxia | C1.1. mutant cell line | C1.1_0hr_cyt_1 |
| PRJNA730029 | GSM5315726 | cytoplasm | normoxia | C1.1. mutant cell line | C1.1_0hr_cyt_2 |
| PRJNA730029 | GSM5315727 | cytoplasm | normoxia | C1.1. mutant cell line | C1.1_0hr_cyt_3 |
| PRJNA730029 | GSM5315728 | cytoplasm | 2h hypoxia | C1.1. mutant cell line | C1.1_2hr_cyt_1 |
| PRJNA730029 | GSM5315729 | cytoplasm | 2h hypoxia | C1.1. mutant cell line | C1.1_2hr_cyt_2 |
| PRJNA730029 | GSM5315730 | cytoplasm | 2h hypoxia | C1.1. mutant cell line | C1.1_2hr_cyt_3 |
| PRJNA730029 | GSM5315731 | cytoplasm | 24h hypoxia | C1.1. mutant cell line | C1.1_24hr_cyt_1 |
| PRJNA730029 | GSM5315732 | cytoplasm | 24h hypoxia | C1.1. mutant cell line | C1.1_24hr_cyt_2 |
| PRJNA730029 | GSM5315733 | cytoplasm | 24h hypoxia | C1.1. mutant cell line | C1.1_24hr_cyt_3 |
| PRJNA730029 | GSM5315734 | nucleus | normoxia | C166 endothelial cell line | C166_0hr_nuc_1 |
| PRJNA730029 | GSM5315735 | nucleus | normoxia | C166 endothelial cell line | C166_0hr_nuc_2 |
| PRJNA730029 | GSM5315736 | nucleus | normoxia | C166 endothelial cell line | C166_0hr_nuc_3 |
| PRJNA730029 | GSM5315737 | nucleus | 2h hypoxia | C166 endothelial cell line | C166_2hr_nuc_1 |
| PRJNA730029 | GSM5315738 | nucleus | 2h hypoxia | C166 endothelial cell line | C166_2hr_nuc_2 |
| PRJNA730029 | GSM5315739 | nucleus | 2h hypoxia | C166 endothelial cell line | C166_2hr_nuc_3 |
| PRJNA730029 | GSM5315740 | nucleus | 24h hypoxia | C166 endothelial cell line | C166_24hr_nuc_1 |
| PRJNA730029 | GSM5315741 | nucleus | 24h hypoxia | C166 endothelial cell line | C166_24hr_nuc_2 |
| PRJNA730029 | GSM5315742 | nucleus | 24h hypoxia | C166 endothelial cell line | C166_24hr_nuc_3 |
| PRJNA730029 | GSM5315743 | nucleus | normoxia | C1.1. mutant cell line | C1.1_0hr_nuc_1 |
| PRJNA730029 | GSM5315744 | nucleus | normoxia | C1.1. mutant cell line | C1.1_0hr_nuc_2 |
| PRJNA730029 | GSM5315745 | nucleus | normoxia | C1.1. mutant cell line | C1.1_0hr_nuc_3 |
| PRJNA730029 | GSM5315746 | nucleus | 2h hypoxia | C1.1. mutant cell line | C1.1_2hr_nuc_1 |
| PRJNA730029 | GSM5315747 | nucleus | 2h hypoxia | C1.1. mutant cell line | C1.1_2hr_nuc_2 |
| PRJNA730029 | GSM5315748 | nucleus | 2h hypoxia | C1.1. mutant cell line | C1.1_2hr_nuc_3 |
| PRJNA730029 | GSM5315749 | nucleus | 24h hypoxia | C1.1. mutant cell line | C1.1_24hr_nuc_1 |
| PRJNA730029 | GSM5315750 | nucleus | 24h hypoxia | C1.1. mutant cell line | C1.1_24hr_nuc_2 |
| PRJNA730029 | GSM5315751 | nucleus | 24h hypoxia | C1.1. mutant cell line | C1.1_24hr_nuc_3 |
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